Angptl4 - angiopoietin-like 4 Gene

Also Known as Arp4; Bk89; Fiaf; Ng27; Pgar; Hfarp; Pgarg; Pp1158

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57875

Summary

Enables enzyme inhibitor activity. Involved in negative regulation of apoptotic process; negative regulation of lipoprotein Lipase activity; and triglyceride homeostasis. Acts upstream of or within negative regulation of endothelial cell apoptotic process. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; integumental system; and musculature. Orthologous to human ANGPTL4 (Angiopoietin Like 4). [provided by Alliance of Genome Resources, Apr 2022]

Angptl4 Products (1)

mRNA Protein Name
NM_020581.2 NP_065606.2 angiopoietin-related protein 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables enzyme inhibitor activity IDA
IDA: Inferred from direct assay
12401877 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of endothelial cell apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
acts upstream of or within negative regulation of endothelial cell apoptotic process IDA
IDA: Inferred from direct assay
10698685 MGI
involved in negative regulation of lipoprotein lipase activity IDA
IDA: Inferred from direct assay
12401877 MGI
involved in triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
19542565 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular region IDA
IDA: Inferred from direct assay
10698685 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
10866690 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-related protein 4

  • 425O18-1

  • angiopoietin-like protein 4

  • fasting-induced adipose factor

  • fibrinogen/angiopoietin-related protein

  • hepatic fibrinogen/angiopoietin-related protein

  • major histocompatibility complex region NG27

  • secreted protein Bk89

Recombinant Angptl4 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P7508 ANGPTL4/Angiopoietin-related 4 Protein, Mouse (HEK293, Fc, solution) Q9Z1P8 (K167-S410) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78237 ANGPTL4/Angiopoietin-related 4 Protein, Mouse (HEK293, His) Q9Z1P8 (R168-S410) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-103325 JTE-907 Activator 98.54% Unkown
Inhibitory Antibodies (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P990335 Anti-ANGPTL4 Antibody Inhibitor 97.18% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angptl4 NCBI NCBI:51129