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Gentulizumab

(Synonyms: Gensci-059)
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Gentulizumab (Gensci-059) is a humanized IgG4 antibody that targets CD47. Gentulizumab displays strong binding to CD47 in both human and monkey, and effectively inhibits the CD47-SIRPα interaction. Gentulizumab exhibits a potent antitumor activity. The isotype control for Gentulizumab can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

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  • Reinheit: 97.02%
  • Molecular Weight:145.97 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Gentulizumab
  • Experimental Validation Results for Gentulizumab
  • Gentulizumab Chemical Structure
    Gentulizumab Chemical Structure
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Gentulizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Gentulizumab (HY-P991062, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized CD47 Protein, Human (HEK293, HY-P72917) can bind Gentulizumab. The EC50 for this effect is 110.4 ng/mL.

  • Gentulizumab Chemical Structure
    1/16
  • Gentulizumab
  • Flow cytometric analysis of 1X106 Jurkat cells with Gentulizumab (HY-P991062, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized CD47 Protein, Human (HEK293, HY-P72917) can bind Gentulizumab. The EC50 for this effect is 110.4 ng/mL.