HDAC3-IN-6
HDAC3-IN-6 (Compound SC26) is a selective HDAC3 inhibitor with an IC50 of 53 nM. HDAC3-IN-6 dose-dependently induces the expression of PD-L1. HDAC3-IN-6 induces more pronounced Apoptosis and production of ROS. HDAC3-IN-6 exhibits high antitumor efficacy against colorectal cancer.
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- CAS. Nr.: 3070532-72-5
- Formel: C23H23N5O3
- Molecular Weight:417.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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HDAC1 3.98 μM (IC50) |
HDAC3 53 nM (IC50) |
Chemical Information
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CAS. Nr. 3070532-72-5
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Molecular Weight 417.46
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Formel C23H23N5O3
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SMILES
O=C(C1=CC=C(CNC(C2=CN=C(C3=CC=C4OC=CC4=C3)N2)=O)C=C1)NNCCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC3-IN-6 Related Classifications
HY-172133 Related Classifications
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