Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
458 Results for "
O2
" in MedChemExpress (MCE) Product Catalog:
Products (458)
458 Results for "O2" in MCE Product Catalog:
Art. -Nr.: HY-N10277
Category:
Target:
Art. -Nr.: HY-N0615R
CAS. Nr.: 80418-24-2
Synonyms: Sanchinoside R1 (Standard); Sanqi glucoside R1 (Standard)
Category:
Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae
Target:
Art. -Nr.: HY-N8788
CAS. Nr.: 675624-38-1
Target:
Art. -Nr.: HY-150563
CAS. Nr.: 2361384-14-5
Target:
Forschungsgebiete:
Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent with an IC50 value of 10.30 μM for MAO-B, and 96.33% inhibition of Aβ1-42 aggregation at 25 μM. Neuroinflammatory-IN-2 has neuroprotective activity in H2O2-induced PC-12 cell injury. Neuroinflammatory-IN-2 also has biometal chelating abilities, antioxidant activity, anti-neuroinflammatory activity and appropriate BBB permeability. Neuroinflammatory-IN-2 can be used for researching Alzheimer’s disease .
Art. -Nr.: HY-W423191
CAS. Nr.: 534-42-9
Synonyms: 4-O-α-D-Glucopyranosyl-D-gluconic acid
Art. -Nr.: HY-D2965
CAS. Nr.: 1219603-04-9
Synonyms: SPG1
Target:
Forschungsgebiete:
CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.
Target:
Forschungsgebiete:
GSK 366 is a type II kynurenine-3-monooxygenase (KMO) inhibitor with IC50 values of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO). GSK 366 binds to KMO’s substrate site, prevents productive NADPH association, substrate binding, and FAD hydroperoxy species formation. GSK 366 does not stimulate hydrogen peroxide (H2O2) production and reduces H2O2 levels. GSK 366 can be used for the researches of inflammation and neurological disease, such as acute pancreatitis multiple organ dysfunction syndrome and Alzheimer’s disease .
Art. -Nr.: HY-114886
CAS. Nr.: 351978-83-1
Target:
Forschungsgebiete:
IGP-5 is a mitochondrial sn-Glycerol 3-phosphate Dehydrogenase (mGPDH) inhibitor with the IC50 of 0.7 μM aganist mGPDH H2O2 production . IGP-5 can be used for study of energy metabolism .
Art. -Nr.: HY-125859B
CAS. Nr.: 9003-99-0
Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H2O2 to catalyze the oxidation of its preferred halide substrates including I −, Br −, F −, or the pseudohalide SCN − .
Art. -Nr.: HY-N2203
CAS. Nr.: 59282-55-2
Category:
other families Flavonoids Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields
Target:
Art. -Nr.: HY-N2627
CAS. Nr.: 53584-69-3
Target:
Art. -Nr.: HY-174868
CAS. Nr.: 3055107-60-0
Forschungsgebiete:
iP300w (Compound 9) is a Histone acetyltransferase p300 (KAT3B) inhibitor. iP300w can be used for synthesis of PROTAC BT-O2C (HY-174866) .
Art. -Nr.: HY-W110905
CAS. Nr.: 19381-50-1
Forschungsgebiete:
Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H2O2 [2].
Art. -Nr.: HY-161783
CAS. Nr.: 3048532-05-1
Forschungsgebiete:
HDAC6-IN-45 (Compound 15) is a selective inhibitor for HDAC6 with IC50 of 15.2 nM. HDAC6-IN-45 exhibits neurotrophic through the upregulation of GAP43 and Beta-3 tubulin markers. HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, inhibits apoptosis in PC12, and exhibits neuroprotective efficacy in SCOP-induced zebrafish Alzheimer's Disease models. HDAC6-IN-45 exhibits antioxidant activity and good blood-brain barrier (BBB) permeability .
Art. -Nr.: HY-P11474
Target:
Integrin FAK Akt ERK Interleukin Related TNF Receptor Bacterial Reactive Oxygen Species (ROS)
Forschungsgebiete:
Art. -Nr.: HY-116730
CAS. Nr.: 886755-63-1
Target:
Forschungsgebiete:
CHS-111 is a benzyl indazole inhibitor of superoxide anion O 2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC50 of 3.9 μM .
Art. -Nr.: HY-151109
Target:
Forschungsgebiete:
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .
Art. -Nr.: HY-119590
CAS. Nr.: 31501-55-0
Synonyms: Lonchocarpine
Lonchocarpin (Lonchocarpine) is a Wnt/β-catenin signaling pathway inhibitor. The IC50 of Lonchocarpin in SW480 pBAR/Renilla cells is 4 μM. Acting downstream of β-catenin stabilization, Lonchocarpin inhibits β-catenin nuclear localization and TCF-mediated transcription, as well as the proliferation and migration of colorectal cancer cells. Lonchocarpin enhances Nrf2/ARE-mediated antioxidant responses in primary astrocytes via AMPK and JNK-related signaling, reduces H2O2-induced ROS production, and increases the expression of HO-1, NQO1 and MnSOD. Lonchocarpin can be used in research on colorectal cancer and oxidative stress [2].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
