468 Results for "

O2

" in MedChemExpress (MCE) Product Catalog:

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HKPerox-1

2 Cited Publications

Cat. No.: HY-130022

CAS No.: 2240163-05-5

Purity: 99.35%

HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H₂O₂ in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively ^[2].

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Cynaroside (Standard)

2 Cited Publications

Cat. No.: HY-N0540R

CAS No.: 5373-11-5

Synonyms: Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)

Category:

Umbelliferae/Apiaceae Extract Plant Anthriscus sylvestris (L.) Hoffm. Extract Flavonoids Flavones Phenols Polyphenols

Target:

Apoptosis DNA/RNA Synthesis Parasite Bacterial Influenza Virus Fungal Reference Standards

Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

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Ophiopogonin D

2 Cited Publications

Cat. No.: HY-N0515

CAS No.: 945619-74-9

Category:

Cardiovascular Disease Plant Ophiopogon japonicus (L. f.) Ker Gawl. Extract Liliaceae Extract Disease Research Fields Asparagaceae Extract Steroids

Target:

PPAR NF-κB Calcium Channel Reactive Oxygen Species (ROS) ERK

Ophiopogonin D can be isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C₂₉ steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca ²⁺ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D can inhibit isteoclastic differentiation in RAW264.7 cells. Ophiopogonin D has protective effect as an antioxidant in H₂O₂-induced endothelial injury. Ophiopogonin D blocks ERK signaling cascades. Ophiopogonin D alleviates high-fat diet-induced metabolic syndrome and changes the structure of gut microbiota in mice. Ophiopogonin D has been used against inflammatory, metabolic and cardiovascular diseases ^[2] .

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Tetrasodium pyrophosphate

2 Cited Publications

Cat. No.: HY-Y1885

CAS No.: 7722-88-5

Tetrasodium pyrophosphate is a water-soluble inorganic salt commonly used as a buffering agent, emulsifier, and sequestrant. Tetrasodium pyrophosphate is an antimicrobial agent that can reduce microbial colonization. Tetrasodium pyrophosphate blocks IPP translocation, enhances astaxanthin, phenol, flavonoid, and H₂O₂ levels, activates PAL and DPPH scavenging activity. Tetrasodium pyrophosphate can be used for the research of alleviating symptoms post COVID-19 ^[2] .

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Efaproxiral

1 Cited Publications

Cat. No.: HY-13619

CAS No.: 131179-95-8

Purity: 99.94%

Synonyms: RSR13

Target:

Hemoglobin

Research Areas:

Infection Cancer

Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy ^[2] .

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Spermidine (Standard)

1 Cited Publications

Cat. No.: HY-B1776R

CAS No.: 124-20-9

Category:

Human Gut Microbiota Metabolites Natural Products Microorganism Endogenous metabolite

Target:

Reference Standards Endogenous Metabolite

Spermidine (Standard) is the analytical standard of Spermidine. This product is intended for research and analytical applications. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents .

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11-oxo-mogroside V

1 Cited Publications

Cat. No.: HY-N0501

CAS No.: 126105-11-1

Category:

Triterpenes Plant Terpenoids Metabolic Disease Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Extract Disease Research Fields Sweeteners Food Research

Target:

Reactive Oxygen Species (ROS)

11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O₂ ^-, H₂O₂ and *OH) with EC₅₀ of 4.79, 16.52, and 146.17 μg/mL, respectively.

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Spermidine-13C4 hydrochloride

1 Cited Publications

Cat. No.: HY-B1776AS1

CAS No.: 1313734-84-7

Spermidine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

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Efaproxiral sodium

1 Cited Publications

Cat. No.: HY-13619A

CAS No.: 170787-99-2

Purity: 99.90%

Synonyms: RSR13 sodium

Target:

Hemoglobin

Research Areas:

Infection Cancer

Efaproxiral (RSR13) sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy ^[2] .

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Spermidine-d6

1 Cited Publications

Cat. No.: HY-B1776S

CAS No.: 2514812-10-1

Spermidine-d₆ is the deuterium labeled Spermidine . Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents ^[2].

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Cathepsin K Antibody

1 Cited Publications

Cat. No.: HY-P81163

Synonyms: Cathepsin K; Procathepsin K; Cathepsin K precursor; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CathepsinK; CTS02; CTSK; CTSK protein; CTSO; CTSO1; CTSO2; MGC23107; PKND; PYCD; Pycnodysostosis; cath-K; CK.

Host:

Rabbit

Application:

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:

Rat

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3-O-(2-Aminoethyl)-25-hydroxyvitamin D3

1 Cited Publications

Cat. No.: HY-15254

CAS No.: 163018-26-6

Purity: 98.46%

Synonyms: 25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether

Target:

VD/VDR

Research Areas:

Metabolic Disease

3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a Vitamin D3 derivative.

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IM-54

1 Cited Publications

Cat. No.: HY-108351

CAS No.: 861891-50-1

Purity: 99.06%

Target:

Necroptosis

Research Areas:

Cardiovascular Disease

IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H₂O₂-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death ^[2].

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Rosamultin

1 Cited Publications

Cat. No.: HY-N2565

CAS No.: 88515-58-6

Category:

Infection Triterpenes Plant Terpenoids Rosaceae Extract Disease Research Fields Potentilla anserina Linn. Extract

Target:

HIV Protease Apoptosis

Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease . Rosamultin has the potential for treating H₂O₂-induced oxidative stress injury through its antioxidant and antiapoptosis effects ^[2].

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TOPS

1 Cited Publications

Cat. No.: HY-15933

CAS No.: 40567-80-4

TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H₂O₂ and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection .

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Sarcosine oxidase, Bacillus

1 Cited Publications

Cat. No.: HY-P2861

CAS No.: 9029-22-5

Synonyms: SAO

Target:

Biochemical Assay Reagents

Research Areas:

Others

Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H₂O₂, 5,10-CH₂-tetrahydrofolate, which are often used in biochemical reactions .

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Veratryl alcohol

1 Cited Publications

Cat. No.: HY-107858

CAS No.: 93-03-8

Purity: 99.98%

Synonyms: 3,4-Dimethoxybenzyl alcohol

Category:

Natural Products Other Diseases Microorganism Disease Research Fields

Target:

Endogenous Metabolite Bacterial

Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy ^[2] .

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3′,4′,7-Trihydroxyflavone

1 Cited Publications

Cat. No.: HY-N2736

CAS No.: 2150-11-0

Category:

Leguminosae/Fabaceae Extract Plant Flavonoids Flavones Other Diseases Phenols Polyphenols Vicia faba L. Extract Disease Research Fields

Target:

Beta-lactamase COX Interleukin Related Bacterial JNK ERK p38 MAPK STAT Apoptosis NO Synthase Nuclear Factor of activated T Cells (NFAT) Lactate Dehydrogenase Reactive Oxygen Species (ROS) SOD Akt Caspase Bcl-2 Family

3′,4′,7-Trihydroxyflavone is an orally active inhibitor of OXA-48 (IC₅₀ = 1.89 μM) and COX-1 (IC₅₀ = 36.37 μM). 3′,4′,7-Trihydroxyflavone exhibits antioxidant and anti-inflammatory properties, inhibiting the release of inflammatory cytokines such as IL-6, IL-8, and TNF-α. 3′,4′,7-Trihydroxyflavone inhibits H₂O₂-induced neuronal apoptosis and ROS accumulation, and exerts anti-neuroinflammatory effects by suppressing the JNK-STAT1 pathway. 3′,4′,7-Trihydroxyflavone exhibits antimicrobial and antibiotic-modifying activities against multidrug-resistant Gram-negative enteric bacteria. 3′,4′,7-Trihydroxyflavone inhibits RANKL-induced osteoclast formation via NFATc1. 3′,4′,7-Trihydroxyflavone activates the CREB-BDNF axis and restores scopolamine (HY-N0296)-induced memory deficits in mice ^[2] .

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RG100204

1 Cited Publications

Cat. No.: HY-161834

CAS No.: 2140901-88-6

Target:

Pyroptosis Aquaporin NOD-like Receptor (NLR) p38 MAPK

Research Areas:

Infection Metabolic Disease Inflammation/Immunology

RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H ²O ². RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice ^[2] .

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TBHBA

1 Cited Publications

Cat. No.: HY-15929

CAS No.: 14348-40-4

Synonyms: 2,4,6-Tribromo-3-hydroxybenzoic acid

TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites ^[2].

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