14348-40-4
Chemical Structure
TBHBA
Synonym(s): 2,4,6-Tribromo-3-hydroxybenzoic acid
- CAS No.: 14348-40-4
- Formula:C7H3Br3O3
- Molecular Weight:374.81
IUPAC Name: 2,4,6-tribromo-3-hydroxybenzoic acid
InChIKey: YDBHVMTTYXWHLI-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(Br)C=C(Br)C(O)=C1Br
Biological Activity: TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H2O2) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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TBHBA | 99.89% | TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H2O2) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites. | ||||||||||||||||||||
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NCR 631 | 97.36% | NCR 631 is a 3-HAO inhibitor and 3-hydroxyanthranilic acid (HY-W001171) analogue. NCR-631 has anticonvulsant properties. NCR-631shows a concentration-dependent protective effect against the anoxia. | ||||||||||||||||||||
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2,5-Dibromoterephtalic acid | 98.10% | 2,5-Dibromoterephtalic acid (2,5-Dibromoterephthalic acid) is a metal-organic framework (MOF). | ||||||||||||||||||||
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4-Bromo-3-hydroxybenzoic acid (Standard) | ≥98% | 4-Bromo-3-hydroxybenzoic acid (Standard) is the analytical standard of 4-Bromo-3-hydroxybenzoic acid (HY-W003445). This product is intended for research and analytical applications. 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes. | ||||||||||||||||||||
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3,5-Dibromo-4-methoxybenzoic acid (Standard) | ≥98% | 3,5-Dibromo-4-methoxybenzoic acid (Standard) is the analytical standard of 3,5-Dibromo-4-methoxybenzoic acid (HY-W038627). This product is intended for research and analytical applications. 3,5-Dibromo-4-methoxybenzoic acid (3,5-Dibromo-p-anisic acid) is a brominated alkaloid that can be isolated from sponges such as Amphimedon sp. and Psammaplysilla purpurea. | ||||||||||||||||||||
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2,6-Dibromoterephthalic acid | 2,6-Dibromoterephthalic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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4,5-Dibromophthalic acid | 4,5-Dibromophthalic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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4,6-Dibromoisophthalic acid | 4,6-Dibromoisophthalic acid (4,6-Dibromobenzene-1,3-dicarboxylic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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2,6-Dibromo-4-(hydroxymethyl)phenol | 2,6-Dibromo-4-(hydroxymethyl) phenol (Compound 5) acts as a selective inhibitor of Saccharomyces cerevisiae glucose-6-phosphate dehydrogenase, with an IC50 value of 50.2 μM, and shows no activity against Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase. | |||||||||||||||||||||
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2,4,6-Tribromo-3-methylphenol | 2,4,6-Tribromo-3-methylphenol is an active compound. | |||||||||||||||||||||
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2,3,4,5-Tetrabromobenzoic acid-13C6 | 2,3,4,5-Tetrabromobenzoic acid-13C6 is 13C labeled 2,3,4,5-Tetrabromobenzoic acid. | |||||||||||||||||||||
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References
- [1]. Moshides JS. Kinetic enzymatic method for automated determination of HDL cholesterol in plasma. J Clin Chem Clin Biochem. 1987 Sep;25(9):583-7. [Content Brief]
- [2]. Mallakpour S, et al. Preparation and characterization of optically active and flame-retardant poly (amide-imide)/SiO2 nanocomposites having N-trimellitylimido-L-methionine linkages using ultrasonic irradiation[J]. Designed Monomers and Polymers, 2015, 18(2): 137-144.
