4-Bromo-3-hydroxybenzoic acid (Standard)
4-Bromo-3-hydroxybenzoic acid (Standard) is the analytical standard of 4-Bromo-3-hydroxybenzoic acid (HY-W003445). This product is intended for research and analytical applications. 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes.
For research use only. We do not sell to patients.
- CAS No.: 14348-38-0
- Formula: C7H5BrO3
- Molecular Weight:217.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 14348-38-0
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Molecular Weight 217.02
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Formula C7H5BrO3
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SMILES
O=C(O)C1=CC=C(Br)C(O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ellenbogen L, et al. Studies on the inhibition of histidine decarboxylase, aromatic-L-amino acid decarboxylase and acid secretion by brocresine and its metabolites. Biochem Pharmacol. 1973 Apr 15;22(8):939-47. [Content Brief]
[2]. Qian S, et al. Inhibiting Histamine Signaling Ameliorates Vertigo Induced by Sleep Deprivation. J Mol Neurosci. 2019 Mar;67(3):411-417. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)