14348-38-0
14348-38-0
Chemical Structure
4-Bromo-3-hydroxybenzoic acid
- CAS No.: 14348-38-0
- Formula:C7H5BrO3
- Molecular Weight:217.02
IUPAC Name: 4-bromo-3-hydroxybenzoic acid
InChIKey: PAJSESFUWIYFNF-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(Br)C(O)=C1
Biological Activity: 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Bromo-3-hydroxybenzoic acid | 99.10% | 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes. | ||||||||||||||||||||
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4-Bromo-3-hydroxybenzoic acid (Standard) | ≥98% | 4-Bromo-3-hydroxybenzoic acid (Standard) is the analytical standard of 4-Bromo-3-hydroxybenzoic acid (HY-W003445). This product is intended for research and analytical applications. 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes. | ||||||||||||||||||||
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References
- [1]. Ellenbogen L, et al. Studies on the inhibition of histidine decarboxylase, aromatic-L-amino acid decarboxylase and acid secretion by brocresine and its metabolites. Biochem Pharmacol. 1973 Apr 15;22(8):939-47. [Content Brief]
- [2]. Qian S, et al. Inhibiting Histamine Signaling Ameliorates Vertigo Induced by Sleep Deprivation. J Mol Neurosci. 2019 Mar;67(3):411-417. [Content Brief]
