10219 Results for "

from

" in MedChemExpress (MCE) Product Catalog:
Products (10219)

10219 Results for "from" in MCE Product Catalog:

582
582 Publications Verification
Art. -Nr.: HY-D1056
Synonyms: LPS, from Escherichia coli (O55:B5)
Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 can be widely used to induce cellular inflammation and establish animal models related to inflammation .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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251
251 Cited Publications
Art. -Nr.: HY-K1001

MCE RIPA Lysis Buffer is one of the most reliable buffers used to lyse cells from both cultured cells and tissues.

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170
170 Cited Publications
Art. -Nr.: HY-16592
CAS. Nr.: 20350-15-6
Synonyms: BFA; Cyanein; Decumbin
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits HSV-1 and has anti-cancer activity .
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161
161 Cited Publications
Art. -Nr.: HY-B0496
CAS. Nr.: 329-98-6
Synonyms: Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
Forschungsgebiete:  

Neurological Disease

PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible serine proteases inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .
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158
158 Cited Publications
Art. -Nr.: HY-Y1888
CAS. Nr.: 8001-30-7
Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
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151
151 Cited Publications
Art. -Nr.: HY-K0013

MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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102
102 Cited Publications
Art. -Nr.: HY-15484
CAS. Nr.: 63208-82-2
Reinheit:  98.58%
Synonyms: Pifithrin hydrobromide; PFTα hydrobromide
Forschungsgebiete:  

Cancer

Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.
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92
92 Cited Publications
Art. -Nr.: HY-N0322
CAS. Nr.: 57-88-5
Cholesterol (from animal) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from animal) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol (from animal) is also an endogenous estrogen-related receptor α (ERRα) agonist .
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79
79 Cited Publications
Art. -Nr.: HY-N0716B
CAS. Nr.: 633-66-9
Synonyms: Natural Yellow 18 sulfate
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
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74
74 Cited Publications
Art. -Nr.: HY-32735
CAS. Nr.: 38748-32-2
Synonyms: PG490
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .
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72
72 Cited Publications
Art. -Nr.: HY-114158
CAS. Nr.: 9036-06-0
Synonyms: Pronase (Activity ≥ 7000 U/g)
Pronase E (Activity ≥ 7000 U/g) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .
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55
55 Cited Publications
Art. -Nr.: HY-100111
CAS. Nr.: 835598-94-2
Reinheit:  99.48%
Target:  

NADPH Oxidase

Forschungsgebiete:  

Metabolic Disease

GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM.
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54
54 Cited Publications
Art. -Nr.: HY-12588
CAS. Nr.: 1009816-48-1
Reinheit:  99.99%
Target:  

OGA Autophagy

Forschungsgebiete:  

Cancer

Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with Ki of 20 nM for human OGA.
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53
53 Cited Publications
Art. -Nr.: HY-13251
CAS. Nr.: 697235-38-4
Reinheit:  99.96%
Synonyms: (-)-Silvestrol
Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
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53
53 Cited Publications
Art. -Nr.: HY-N0716A
CAS. Nr.: 316-41-6
Synonyms: Natural Yellow 18 hemisulfate
Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
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50
50 Cited Publications
Art. -Nr.: HY-B2167
CAS. Nr.: 6217-54-5
Synonyms: DHA; Cervonic acid
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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50
50 Cited Publications
Art. -Nr.: HY-109025A
CAS. Nr.: 1985605-59-1
Reinheit:  99.68%
Synonyms: Baloxavir acid; S-033447
Target:  

Influenza Virus

Forschungsgebiete:  

Infection Cancer

Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity .
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47
47 Cited Publications
Art. -Nr.: HY-N0174
CAS. Nr.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
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42
42 Cited Publications
Art. -Nr.: HY-N0431
CAS. Nr.: 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
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41
41 Cited Publications
Art. -Nr.: HY-15743
CAS. Nr.: 202590-98-5
Reinheit:  99.75%
Synonyms: OTX-015; MK-8628
Forschungsgebiete:  

Cancer

Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM.
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