Antitumor agent-97
Antitumor agent-97 (compound 42) is an anticancer agent. Antitumor agent-97 can effectively inhibit the proliferation and autophagy of MGC 803 cells, and induce apoptosis. Antitumor agent-97 also enhances ROS accumulation in MGC 803 cells. Antitumor agent-97 can be used in cancer research.
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- CAS No.: 2654024-16-3
- Formule: C24H34O3
- Masse moléculaire:370.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Antitumor agent-97 (Compound 42; 0-200 μM; 24 h) inhibits cell viability of MGC 803 cells in a dose-dependent manner, with an IC50 value of 20.921 μM[1].
Antitumor agent-97 (20 μM; 24 h) decreases cell proliferation of MGC 803 cells[1].
Antitumor agent-97 (20 μM; 24 h) induces apoptosis and inhibits autophagy in MGC 803 cells[1].
Antitumor agent-97 (20 μM; 0-24 h) enhances ROS accumulation in MGC 803 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MGC 803 cells
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Concentration:0-200 μM
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Incubation Time:24 h
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Result:Suppressed cell viability (IC50 = 20.921 μM).
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Cell Line:MGC 803 cells
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Concentration:20 μM
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Incubation Time:24 h
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Result:Inhibited cell proliferation.
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Cell Line:MGC 803 cells
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Concentration:20 μM
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Incubation Time:24 h
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Result:Significantly upregulated the protein expression of LC3B-II and p62 and decreased the protein expression of LC3B-I.
Enhanced the protein expression of cleaved caspase-9 and cleaved caspase-3, and decreased the protein expression of B-cell lymphoma-2 (Bcl-2).
Chemical Information
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CAS No. 2654024-16-3
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Masse moléculaire 370.52
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Formule C24H34O3
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SMILES
C[C@@]12[C@](CCC3=CC(C(C)C)=CC=C32)([H])[C@](C)([C@H](CC1)O)COC(C4CC4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-97 Related Classifications
HY-149829 Related Classifications
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