Plafibride
Plafibride (ITA 104) is an orally active hypolipemic, platelet aggregation inhibitor.
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- CAS No.: 63394-05-8
- Formule: C16H22ClN3O4
- Masse moléculaire:355.82
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Plafibride has low toxicity, with LD50s of about 4000 mg/kg (p.o.) in rat, mouse and hamster[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rabbit[1]
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Dosage:100 mg/kg
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Administration:Oral administration (p.o.)
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Result:Induced platelet aggregation.
Chemical Information
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CAS No. 63394-05-8
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Masse moléculaire 355.82
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Formule C16H22ClN3O4
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SMILES
O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(Cl)C=C2)=O
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Synonyms
ITA 104
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]
[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Plafibride Related Classifications
HY-106580 Related Classifications
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