Plafibride hydrochloride
Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 65285-81-6
- Formula: C16H23Cl2N3O4
- Molecular Weight:392.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Plafibride hydrochloride has low toxicity, with LD50s of about 4000 mg/kg (p.o.) in rat, mouse and hamster[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rabbit[1]
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Dosage:100 mg/kg
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Administration:Oral administration (p.o.)
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Result:Induced platelet aggregation.
Chemical Information
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CAS No. 65285-81-6
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Molecular Weight 392.28
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Formula C16H23Cl2N3O4
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SMILES
O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(C=C2)Cl)=O.Cl
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Synonyms
ITA 104 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]
[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Plafibride hydrochloride Related Classifications
HY-106580A Related Classifications
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