1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. Dexpramipexole

Dexpramipexole (Synonyms: (R)-Pramipexole; R-(+)-Pramipexole; KNS-760704)

Cat. No.: HY-17355B
Handling Instructions

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist.

For research use only. We do not sell to patients.

Dexpramipexole Chemical Structure

Dexpramipexole Chemical Structure

CAS No. : 104632-28-2

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Description

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. IC50 Value: Target: Dopamine Receptor Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity.

Clinical Trial
Molecular Weight

211.33

Formula

C10H17N3S

CAS No.
SMILES

NC1=NC(CC[[email protected]@H](NCCC)C2)=C2S1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Dexpramipexole
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