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Cat. No.: HY-168233

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E3 Ligase Ligand-linker Conjugate 124

E3 Ligase Ligand-linker Conjugate 124 is an E3 ubiquitinase ligand + linker conjugate. E3 Ligase Ligand-linker Conjugate 124 can be used to synthesize PROTAC SMARCA2 degrader-27 (HY-168229).

For research use only. We do not sell to patients.

Formula: C₃₇H₅₁FN₆O₆
Molecular Weight:694.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

E3 Ligase Ligand-linker Conjugate 124 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 124 is an E3 ubiquitinase ligand + linker conjugate. E3 Ligase Ligand-linker Conjugate 124 can be used to synthesize PROTAC SMARCA2 degrader-27 (HY-168229)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 694.84
Formula C₃₇H₅₁FN₆O₆
SMILES

CC(C)[C@@H](C(N1C[C@H](O)C[C@H]1C(N[C@H](C2=CC(F)=C(C#N)C=C2)C)=O)=O)C3=CC(N4CCC(CC4)CN(CC5)CCC5O[C@@H](C6)C[C@H]6O)=NO3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Michael Berlin, et al. Brm targeting compounds and associated methods of use. WO2023097031.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

E3 Ligase Ligand-linker Conjugate 124

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E3 Ligase Ligand-linker Conjugate 124

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 124 Related Classifications

HY-168233 Related Classifications

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