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Referencia número: HY-N20724

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Ageconyflavone C

Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC₅₀ values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research.

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No. CAS: 93124-90-4
Fòrmula: C₂₀H₂₀O₈
Peso molecular:388.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

Ageconyflavone C Chemical Structure

No. CAS: 93124-90-4

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In Vitro

Ageconyflavone C (compound 5) (>30 μg/mL; >90 μg/mL) exhibits moderate in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense (IC₅₀ = 7.8 μM), Leishmania donovani (IC₅₀ = 9.2 μM), and Plasmodium falciparum (IC₅₀ = 9.25 μM), with no activity against Trypanosoma cruzi and no cytotoxicity against L6 rat skeletal myoblasts at the highest tested concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 93124-90-4
Peso molecular 388.37
Fòrmula C₂₀H₂₀O₈
SMILES

O=C1C=C(C2=CC(OC)=C(O)C(OC)=C2)OC3=C1C(OC)=C(OC)C(OC)=C3
Structure Classification
- Flavonoids
- Flavonols
- Phenols
- Monophenols
Initial Source
- Plants
- Compositae
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Nour AM, et al. The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. Journal of ethnopharmacology. 2010 May 04;129(1):127-30. [Content Brief]

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Ageconyflavone C

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