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Etrolizumab

(Synonyms: rhuMAb Beta7; RG7413; PRO145223)
2 Cited Publications
Revisión del cliente

Based on 2 publication(s) in Google Scholar

Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with Ki values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD).

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  • Pureza: 99.56%
  • No. CAS: 1044758-60-2
  • Peso molecular:144.3 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Etrolizumab
  • Experimental Validation Results for Etrolizumab
  • Etrolizumab Chemical Structure
    Etrolizumab Chemical Structure
No. CAS: 1044758-60-2
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Etrolizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Etrolizumab (HY-P9984, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1(D356E/L358M) kappa Isotype Control (HY-P990100, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Etrolizumab Chemical Structure
    1/16
  • Etrolizumab
  • Flow cytometric analysis of 1X106 Jurkat cells with Etrolizumab (HY-P9984, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1(D356E/L358M) kappa Isotype Control (HY-P990100, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).