Quinacrine acetate
Based on 4 publication(s) in Google Scholar
Quinacrine (Acriquine) acetate is a small molecule modulator of the cGAS-STING-TBK1 signaling pathway, possessing immune stimulatory activity. Quinacrine acetate has been explored for its potential therapeutic applications in enhancing anti-tumor immunity. Quinacrine acetate can improve the effectiveness of cancer immunotherapies by addressing the poor immunogenicity of various tumors. Quinacrine acetate also presents a promising strategy for overcoming the limitations associated with immune checkpoint inhibitors in cancer treatment.
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- No. CAS: 78901-94-7
- Fòrmula: C25H34ClN3O3
- Peso molecular:460.01
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Quinacrine acetate
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Actividad biológica
Chemical Information
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No. CAS 78901-94-7
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Peso molecular 460.01
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Fòrmula C25H34ClN3O3
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SMILES
O=C(C)O.ClC(C=CC1=C2NC(CCCN(CC)CC)C)=CC1=NC3=C2C=C(OC)C=C3
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Synonyms
Acriquine acetate
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
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J Neuroinflammation
2025 Oct 27;22(1):243. PMID: 41146204 -
Phytomedicine
Quinacrine induces autophagy via the Dlg5/AKT pathway to inhibit osteosarcoma cell proliferation and suppresses migration and invasion through the Dlg5/Girdin pathway. [Abstract]2025 Sep:145:156981. PMID: 40541124 -
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Brain Behav Immun
Inhibition of the NFATc2/FKBP5 axis alleviates microglial neuroinflammation by regulating arachidonic acid metabolism in Parkinson's disease. [Abstract]2026 Jan 18:134:106296. PMID: 41554345
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)