BACE2 - beta-secretase 2 Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100517374

About BACE2

Primary_assembly 13: 204,600,735-204,695,316 forward strand.Sscrofa11.1:CM000824.5

This gene has 3 transcripts (splice variants), 204 orthologues and 20 paralogues. Ubiquitous expression in kidney (RPKM 3.8), liver (RPKM 2.1) and 8 other tissues.

BACE2 Products (5)

mRNA Protein Name
XM_021071002.1 XP_020926661.1 beta-secretase 2 isoform X1
XM_021071004.1 XP_020926663.1 beta-secretase 2 isoform X2
XM_021071006.1 XP_020926665.1 beta-secretase 2 isoform X4
XM_021071005.1 XP_020926664.1 beta-secretase 2 isoform X3
XM_005670363.3 XP_005670420.1 beta-secretase 2 isoform X5

BACE2 Protein Structure

beta_secretase_like

beta_secretase_like: cd05473 (84 - 445)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 514 a.a.
Protein Preferred Names Protein Names

beta-secretase 2

  • beta-site APP-cleaving enzyme 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16759 Verubecestat Inhibitor 99.56% Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136742 BACE2-IN-1 Inhibitor 99.4% Unkown
HY-124322 NB-360 Inhibitor 99.08% Unkown
HY-12938 AMG-8718 Inhibitor / Unkown
HY-161359 BACE1-IN-14 Inhibitor / Unkown
HY-147758 BACE1/2-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BACE2 NCBI NCBI:25825
Mus musculus BACE2 NCBI NCBI:56175