1. Neuronal Signaling
  2. Beta-secretase

BACE1-IN-1 

Cat. No.: HY-100182
Handling Instructions

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

For research use only. We do not sell to patients.

BACE1-IN-1 Chemical Structure

BACE1-IN-1 Chemical Structure

CAS No. : 1310347-50-2

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1 mg USD 1315 Get quote
5 mg USD 2104 Get quote
10 mg USD 3366 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

IC50 & Target

IC50: 32 nM (human BACE1), 47 nM (human BACE2)[1]

References
Molecular Weight

389.33

Formula

C₁₈H₁₄F₃N₅O₂

CAS No.

1310347-50-2

SMILES

O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([[email protected]@]3(C)N=C(N)OCC3(F)F)=C2

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BACE1-IN-1
Cat. No.:
HY-100182
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BACE1-IN-1

Cat. No.: HY-100182