1. Neuronal Signaling
  2. Beta-secretase
  3. BACE1-IN-1

BACE1-IN-1 

Cat. No.: HY-100182
Handling Instructions

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

For research use only. We do not sell to patients.

BACE1-IN-1 Chemical Structure

BACE1-IN-1 Chemical Structure

CAS No. : 1310347-50-2

Size Price Stock
1 mg USD 1315 Ask For Quote & Lead Time
5 mg USD 2104 Ask For Quote & Lead Time
10 mg USD 3366 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

IC50 & Target

IC50: 32 nM (human BACE1), 47 nM (human BACE2)[1]

Molecular Weight

389.33

Formula

C₁₈H₁₄F₃N₅O₂

CAS No.

1310347-50-2

SMILES

O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([[email protected]@]3(C)N=C(N)OCC3(F)F)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
BACE1-IN-1
Cat. No.:
HY-100182
Quantity:
MCE Japan Authorized Agent: