1310347-50-2
1310347-50-2
Chemical Structure
BACE1-IN-1
- CAS No.: 1310347-50-2
- Formula:C18H14F3N5O2
- Molecular Weight:389.33
IUPAC Name: (R)-N-(3-(2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide
InChIKey: DVMUZHLUMHPCGZ-QGZVFWFLSA-N
SMILES: O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2
Biological Activity: BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
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BACE1-IN-1 | 98.72% | BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. | ||||||||||||||||||||
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BACE1-IN-1 (Standard) | ≥98% | BACE1-IN-1 (Standard) is the analytical standard of BACE1-IN-1 (HY-100182). This product is intended for research and analytical applications. BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. | ||||||||||||||||||||
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Keywords
