1. Neuronal Signaling
  2. Beta-secretase
  3. BACE-1 inhibitor 1

BACE-1 inhibitor 1 

Cat. No.: HY-112297
Handling Instructions

BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM.

For research use only. We do not sell to patients.

BACE-1 inhibitor 1 Chemical Structure

BACE-1 inhibitor 1 Chemical Structure

CAS No. : 1262858-14-9

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Description

BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].

IC50 & Target

IC50: 56 nM (BACE-1)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

443.22

Formula

C₁₇H₁₄BrF₃N₄O₂

CAS No.

1262858-14-9

SMILES

BrC1=CC=C(C(NC2=CC=C(F)C([[email protected]@]3(C(F)F)N=C(N)COC3)=C2)=O)N=C1

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BACE-1 inhibitor 1
Cat. No.:
HY-112297
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BACE-1 inhibitor 1

Cat. No.: HY-112297