MELK - maternal embryonic leucine zipper kinase Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100519998

About MELK

Primary_assembly 1: 237,317,191-237,431,589 forward strand.Sscrofa11.1:CM000812.5

This gene has 6 transcripts (splice variants), 217 orthologues and 17 paralogues. Biased expression in ovary (RPKM 32.6), spleen (RPKM 4.3) and 1 other tissue.

MELK Products (5)

mRNA Protein Name
XM_005660248.3 XP_005660305.1 maternal embryonic leucine zipper kinase isoform X1
XM_021066072.1 XP_020921731.1 maternal embryonic leucine zipper kinase isoform X1
XM_013993665.2 XP_013849119.1 maternal embryonic leucine zipper kinase isoform X1
XM_003480551.4 XP_003480599.1 maternal embryonic leucine zipper kinase isoform X1
XM_021066086.1 XP_020921745.1 maternal embryonic leucine zipper kinase isoform X2

MELK Protein Structure

STKc_MELK

STKc_MELK: cd14078 (6 - 262)

UBA_MELK

UBA_MELK: cd14341 (280 - 331)

MELK_C

MELK_C: cd12198 (553 - 647)

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  • 650 a.a.
Protein Preferred Names Protein Names

maternal embryonic leucine zipper kinase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15512 OTSSP167 Inhibitor 99.27% Phase 2
HY-15512A OTSSP167 hydrochloride Inhibitor 99.78% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100368A MELK-8a hydrochloride Inhibitor 99.31% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-101515 MELK-IN-1 Inhibitor 98.03% Unkown
HY-12420 JNJ-47117096 hydrochloride Inhibitor 99.67% Unkown
HY-122665 HTH-01-091 Inhibitor 99.81% Unkown
HY-100368 MELK-8a Inhibitor 98.32% Unkown
HY-122665A HTH-01-091 TFA Inhibitor 99.48% Unkown
HY-155748 Antitumor agent-116 Inhibitor / Unkown
HY-N17632 Moracin G Inhibitor / Unkown
HY-12420A JNJ-47117096 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MELK NCBI NCBI:9833