PLK4 - polo like kinase 4 Gene

Macaca fascicularis

Gene ID: 101866828 | Gene type: protein coding

About PLK4

Primary_assembly 5: 124,848,941-124,867,422 forward strand.Macaca_fascicularis_6.0:CM021943.1

This gene has 2 transcripts (splice variants), 210 orthologues and 4 paralogues.

mRNA	Protein	Name
XM_045392857.1	XP_045248792.1	serine/threonine-protein kinase PLK4 isoform X2
XM_015450810.2	XP_015306296.1	serine/threonine-protein kinase PLK4 isoform X3
XM_005555891.3	XP_005555948.1	serine/threonine-protein kinase PLK4 isoform X5
XM_005555889.3	XP_005555946.1	serine/threonine-protein kinase PLK4 isoform X1
XM_045392858.1	XP_045248793.1	serine/threonine-protein kinase PLK4 isoform X4

STKc_PLK4

POLO_box_Plk4_1

Plk4_PB2

POLO_box_Plk4_3

Protein Preferred Names

Protein Names

serine/threonine-protein kinase PLK4

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-12300	Ocifisertib	Inhibitor	99.78%	Phase 2
HY-12300B	Ocifisertib fumarate	Inhibitor	98.69%	Phase 2
HY-172737	RP-1664	Inhibitor	98.77%	Phase 1

Pre-clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-18682	Centrinone	Inhibitor	98.28%	Unkown
HY-100789	ON1231320	Inhibitor	99.90%	Unkown
HY-18683	Centrinone-B	Inhibitor	98.65%	Unkown
HY-128493	PLK4-IN-4	Inhibitor	99.89%	Unkown
HY-132135	(1E)-CFI-400437 dihydrochloride	Inhibitor	98.08%	Unkown
HY-149912	CZS-241	Inhibitor	/	Unkown
HY-176734	CZL-S092	Inhibitor	/	Unkown
HY-134775A	PLK4-IN-3	Inhibitor	/	Unkown
HY-179149	PLK4-IN-6	Inhibitor	/	Unkown
HY-115589	YLT-11	Inhibitor	/	Unkown
HY-180111	PLK4-IN-7	Inhibitor	/	Unkown
HY-12300A	Ocifisertib hydrochloride	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	PLK4	NCBI	NCBI:10733

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