Jmjd1c - jumonji domain containing 1C Gene

Also Known as TRIP8; Jmjdic; 5430433L24Rik; D630035I23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108829

Summary

Predicted to enable chromatin DNA binding activity; histone H3-methyl-lysine-9 demethylase activity; and transcription coregulator activity. Acts upstream of or within several processes, including male germ-line stem cell population maintenance; reproductive senescence; and seminiferous tubule development. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex. Predicted to be active in chromatin. Is expressed in several structures, including central nervous system; genitourinary system; heart; inner ear; and limb. Orthologous to human JMJD1C (jumonji domain containing 1C). [provided by Alliance of Genome Resources, Apr 2022]

Jmjd1c Products (4)

mRNA Protein Name
NM_001242396.1 NP_001229325.1 probable JmjC domain-containing histone demethylation protein 2C isoform 2
NM_207221.3 NP_997104.2 probable JmjC domain-containing histone demethylation protein 2C isoform 1
NM_001242396.1 NP_001229325.1 probable JmjC domain-containing histone demethylation protein 2C isoform 2
NM_207221.3 NP_997104.2 probable JmjC domain-containing histone demethylation protein 2C isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within epithelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
24006281 MGI
acts upstream of or within maintenance of cell number IMP
IMP: Inferred from mutant phenotype
24006281 MGI
acts upstream of or within male germ-line stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
24006281 MGI
acts upstream of or within male gonad development IMP
IMP: Inferred from mutant phenotype
24006281 MGI
acts upstream of or within reproductive senescence IMP
IMP: Inferred from mutant phenotype
24006281 MGI
acts upstream of or within seminiferous tubule development IMP
IMP: Inferred from mutant phenotype
24006281 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable JmjC domain-containing histone demethylation protein 2C

  • jumonji domain-containing protein 1C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162275 JMJD1C-IN-1 99.96% Unkown
HY-RS16249 Jmjd1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07037 JMJD1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24674 Jmjd1c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jmjd1c NCBI NCBI:221037