Ugt1a6 - UDP glucuronosyltransferase family 1 member A6 Gene

Also Known as Ugt1; Udpgt; Ugt1a7; UDPGT 1-6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 113992

Summary

Enables glucuronosyltransferase activity. Involved in several processes, including 4-chlorobiphenyl metabolic process; cellular response to glucocorticoid stimulus; and response to lipopolysaccharide. Located in intracellular membrane-bounded organelle. Part of protein-containing complex. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human UGT1A6 (UDP glucuronosyltransferase family 1 member A6). [provided by Alliance of Genome Resources, Apr 2022]

Ugt1a6 Products (4)

mRNA Protein Name
NM_001039691.3 NP_001034780.1 UDP-glucuronosyltransferase 1-6 precursor
NM_057105.3 NP_476446.2 UDP-glucuronosyltransferase 1-6 precursor
NM_001039691.3 NP_001034780.1 UDP-glucuronosyltransferase 1月6日 precursor
NM_057105.3 NP_476446.2 UDP-glucuronosyltransferase 1月6日 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glucuronosyltransferase activity IDA
IDA: Inferred from direct assay
11854153 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
17965520 RGD
Biological Process GO Annotation Evidence References Source
involved in 4-chlorobiphenyl metabolic process IDA
IDA: Inferred from direct assay
16006569 RGD
involved in cellular response to glucocorticoid stimulus IDA
IDA: Inferred from direct assay
18039810 RGD
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
10100302 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
18938141 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
19356101 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
10845702 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
11408524 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
17965520 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

UDP-glucuronosyltransferase 1-6

  • A1

  • P-nitrophenol specific

  • P-nitrophenol-specific UDPGT

  • UDP glucuronosyltransferase 1 family, polypeptide A6

  • UDP glucuronosyltransferase 1A6

  • UDP glycosyltransferase 1 family, polypeptide A6

  • UGT1*6

  • UGT1-06

  • UGT1.6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-119323 7-Azido-4-methylcoumarin 98.90% Unkown
HY-N13388 5-Hydroxytryptophol-O-glucuronide 99.86% Unkown
HY-RS15430 UGT1A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W777236 N-Acetyl serotonin β-D-glucuronide / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ugt1a6 NCBI NCBI:54578