2. Gene
  3. Kiss1r - KISS1 receptor Gene

Kiss1r - KISS1 receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gpr54; KiSS-1; kiSS-1R

Gene ID: 114229 | Gene type: protein coding

About Kiss1r

Chromosome 10: 79,752,805-79,758,107 forward strand.GRCm39:CM001003.3

This gene has 3 transcripts (splice variants), 135 orthologues, 15 paralogues and is associated with 135 phenotypes. Ubiquitous expression in lung adult (RPKM 3.2), adrenal adult (RPKM 2.2) and 26 other tissues.

Summary

Enables G protein-coupled peptide receptor activity. Acts upstream of or within negative regulation of cell migration; negative regulation of cell population proliferation; and signal transduction. Located in cell surface. Is expressed in alimentary system; brain; genitourinary system; sensory organ; and thymus. Used to study hypogonadotropic hypogonadism 8 with or without anosmia. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Kiss1r Products(2)

mRNA Protein Name
NM_053244.5 NP_444474.1 kiSS-1 receptor isoform 1
NM_001359010.1 NP_001345939.1 kiSS-1 receptor isoform 2

Kiss1r Protein Structure

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (42 - 333)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (43 - 69)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (76 - 102)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (114 - 144)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (156 - 176)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (200 - 229)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (255 - 285)

7tmA_KiSS1R

7tmA_KiSS1R: cd15095 (301 - 326)

  • 0
  • 100
  • 200
  • 300
  • 396 a.a.
Protein Preferred Names Protein Names

kiSS-1 receptor

G-protein coupled receptor 54

G-protein coupled receptor OT7T175

kisspeptins receptor

metastin receptor

orphan G protein-coupled receptor 54

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P0076A TAK-448 acetate 98.87% Phase 2
HY-P0076 TAK-448 / Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P2161B TAK-683 acetate 98.97% Unkown
HY-P2161 TAK-683 / Unkown
HY-P2161A TAK-683 TFA / Unkown
HY-RS07316 KISS1R Human Pre-designed siRNA Set A / Unkown
HY-RS07317 Kiss1r Mouse Pre-designed siRNA Set A / Unkown
HY-RS07318 Kiss1r Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kiss1r NCBI NCBI:84634