Acp5 - acid phosphatase 5, tartrate resistant Gene

Also Known as TRAP; TRACP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11433

Summary

Enables Acid Phosphatase activity. Acts upstream of or within several processes, including bone resorption; negative regulation of cytokine production; and response to bacterium. Located in lysosome. Is expressed in several structures, including alimentary system; limb; liver; skeleton; and skin. Orthologous to human ACP5 (Acid Phosphatase 5, tartrate resistant). [provided by Alliance of Genome Resources, Apr 2022]

Acp5 Products (3)

mRNA Protein Name
NM_001102404.1 NP_001095874.1 tartrate-resistant acid phosphatase type 5 precursor
NM_001102405.1 NP_001095875.1 tartrate-resistant acid phosphatase type 5 precursor
NM_007388.3 NP_031414.1 tartrate-resistant acid phosphatase type 5 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acid phosphatase activity IDA
IDA: Inferred from direct assay
9308894 MGI
enables acid phosphatase activity IMP
IMP: Inferred from mutant phenotype
8898228 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within bone morphogenesis IMP
IMP: Inferred from mutant phenotype
8898228 MGI
acts upstream of or within bone resorption IMP
IMP: Inferred from mutant phenotype
8898228 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within dephosphorylation IDA
IDA: Inferred from direct assay
9308894 MGI
acts upstream of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of interleukin-12 production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of interleukin-12 production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of superoxide anion generation IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within negative regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of or within response to cytokine IDA
IDA: Inferred from direct assay
8200916 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of superoxide anion generation IMP
IMP: Inferred from mutant phenotype
11168643 MGI
acts upstream of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
11168643 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
11168643 MGI
located in lysosome IMP
IMP: Inferred from mutant phenotype
11731469 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tartrate-resistant acid phosphatase type 5

  • TR-AP

  • acid phosphatase type V

  • tartrate-resistant acid ATPase

  • trATPase

  • type 5 acid phosphatase

Recombinant Acp5 Proteins

Cat. No. Product Name Accession Purity
HY-P75540 ACP5 Protein, Mouse (HEK293, His) Q05117 (A23-P327) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-138869 AubipyOMe 99.0% Unkown
HY-117200 Necrostatin-7 Inhibitor 99.64% Unkown
HY-124663 CBK289001 Inhibitor 99.74% Unkown
HY-RS00190 ACP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17325 Acp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23780 Acp5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acp5 NCBI NCBI:54