ACP5
ACP5 encodes tartrate-resistant acid phosphatase (TRAP), a binuclear iron-containing acid phosphatase secreted by osteoclasts and activated macrophages. Uniquely among acid phosphatases, its activity is not inhibited by tartrate, and in bone-resorbing osteoclasts it is delivered in ruffled-border vesicles, where it can dephosphorylate matrix proteins such as osteopontin during resorption. Serum TRAP5b is an established clinical marker of osteoclast number and bone resorption used in osteoporosis management, and TRAP also contributes to macrophage functions in inflammation and immunity. Recombinant ACP5 is employed in tartrate-resistance enzyme assays, bone turnover biomarker development, and histochemical detection of osteoclasts.
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ACP5 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
