2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. CBK289001

CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively.

For research use only. We do not sell to patients.

CBK289001 Chemical Structure

CBK289001 Chemical Structure

CAS No. : 1212663-24-5

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CBK289001 Related Antibodies

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Description

CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively[1].

In Vitro

Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 µM or 100 µM[1].
CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CBK289001 Related Antibodies
Molecular Weight

396.40

Formula

C19H20N6O4
CAS No.
SMILES

O=C(N1[C@H](C2=NC(C3=CC=C(OCO4)C4=C3)=NO2)CC5=C(NC=N5)C1)NC(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CBK289001 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CBK2890011212663-24-5CBK 289001CBK-289001Protease Activated Receptor (PAR)Thrombin receptorsTRAPACP5migrationanticancerInhibitorinhibitorinhibit

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