2. Gene
  3. UBE2J2 - ubiquitin conjugating enzyme E2 J2 Gene

UBE2J2 - ubiquitin conjugating enzyme E2 J2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UBC6; NCUBE2; NCUBE-2; PRO2121

Gene ID: 118424 | Gene type: protein coding

About UBE2J2

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,253,912-1,273,854 (from NCBI)

This gene has 20 transcripts (splice variants), 208 orthologues and 24 paralogues. Broad expression in testis (RPKM 15.7), fat (RPKM 6.0) and 25 other tissues.

Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating Enzyme family. This Enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

UBE2J2 Products(4)

mRNA Protein Name
NM_058167.3 NP_477515.2 ubiquitin-conjugating enzyme E2 J2 isoform 2
NM_194315.2 NP_919296.1 ubiquitin-conjugating enzyme E2 J2 isoform 1
NM_194457.2 NP_919439.1 ubiquitin-conjugating enzyme E2 J2 isoform 3
NM_194458.2 NP_919440.1 ubiquitin-conjugating enzyme E2 J2 isoform 3

UBE2J2 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (16 - 129)

  • 0
  • 100
  • 200
  • 259 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 J2

E2 ubiquitin-conjugating enzyme J2

Recombinant UBE2J2 Proteins

Cat. No. Product Name Accession Purity
HY-P71404 UBE2J2 Protein, Human (GST) Q8N2K1 (E124-R224) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15351 UBE2J2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta UBE2J2 VGNC VGNC:79189
Bos taurus UBE2J2 VGNC VGNC:36586
Rattus norvegicus UBE2J2 RGD RGD:1359523
Mus musculus UBE2J2 MGD MGI:2153608
Canis familiaris UBE2J2 VGNC VGNC:48056
Felis catus UBE2J2 VGNC VGNC:107687
Others UBE2J2 NCBI