Coch - cochlin Gene

Also Known as Coch-5B2; D12H14S564E

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12810

Summary

Predicted to enable Collagen binding activity. Acts upstream of or within defense response to bacterium; positive regulation of innate immune response; and sensory perception of sound. Located in extracellular matrix and extracellular region. Is expressed in central nervous system; inner ear; olfactory epithelium; and vibrissa. Used to study autosomal dominant nonsyndromic deafness 9. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 9 and autosomal recessive nonsyndromic deafness 110. Orthologous to human COCH (cochlin). [provided by Alliance of Genome Resources, Apr 2022]

Coch Products (8)

mRNA Protein Name
NM_001198835.2 NP_001185764.1 cochlin isoform 2 precursor
NM_001409459.1 NP_001396388.1 cochlin isoform 1 precursor
NM_001409460.1 NP_001396389.1 cochlin isoform 3 precursor
NM_001409461.1 NP_001396390.1 cochlin isoform 4 precursor
NM_001409462.1 NP_001396391.1 cochlin isoform 5 precursor
NM_001409463.1 NP_001396392.1 cochlin isoform 6 precursor
NM_001409464.1 NP_001396393.1 cochlin isoform 7 precursor
NM_007728.6 NP_031754.1 cochlin isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
23684986 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
21073934 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
11709536 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cochlin

  • coagulation factor C homolog (Limulus polyphemus)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-W391701 Pomalidomide-COCH2Cl 98.52% Unkown
HY-174799 HSP90i-COCH2CH2-PEG4-NHBoc Ligand / Unkown
HY-176536 (S,R,S)-AHPC-amide-PEG5-C2-azide / Unkown
HY-184563S (2S,10S,19S)-Amine-(CO-CH2-N-Me)9-CO-CH2-CH(NH-CO-CH2-CH2-2-piperidone-tetrahydropyran-pyrimidine-SO2-cyclopentane)-(CO-NH-CH2)2-CO-NH-CH(CH2-benzene)-(CO-NH-CH2)2-O-CH(cyclopropane)-COOH-7-MAD-MDCPT-d2 / Unkown
HY-RS02949 COCH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-163647 Lenalidomide-COCH-PEG2-azido / Unkown
HY-RS18920 Coch Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25410 Coch Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Coch NCBI NCBI:1690