Dgka - diacylglycerol kinase, alpha Gene

Also Known as 80kDa; Dagk1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13139

Summary

Enables diacylglycerol kinase activity and phospholipid binding activity. Predicted to be involved in glycerolipid metabolic process; intracellular signal transduction; and lipid phosphorylation. Predicted to act upstream of or within lipid metabolic process and phosphorylation. Located in cytosol and plasma membrane. Is expressed in several structures, including alimentary system; cranial ganglion; integumental system; respiratory system; and sensory organ. Orthologous to human DGKA (diacylglycerol kinase alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dgka Products (5)

mRNA Protein Name
NM_001358745.1 NP_001345674.1 diacylglycerol kinase alpha isoform 1
NM_001358746.1 NP_001345675.1 diacylglycerol kinase alpha isoform 1
NM_001372366.1 NP_001359295.1 diacylglycerol kinase alpha isoform 2
NM_001374028.1 NP_001360957.1 diacylglycerol kinase alpha isoform 3
NM_016811.3 NP_058091.2 diacylglycerol kinase alpha isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP-dependent diacylglycerol kinase activity IDA
IDA: Inferred from direct assay
12832407 MGI
enables phospholipid binding IDA
IDA: Inferred from direct assay
12832407 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
12832407 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12832407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

diacylglycerol kinase alpha

  • 80 kDa diacylglycerol kinase

  • DAG kinase alpha

  • DGK-alpha

  • diacylglycerol kinase alpha Flt2-Pr2

  • diglyceride kinase alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135898 DGK-IN-1 Inhibitor 98.67% Unkown
HY-117168 1,2-Dilinoleoyl-sn-glycerol 97.09% Unkown
HY-RS03715 DGKA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18236 Dgka Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24715 Dgka Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dgka NCBI NCBI:1606