2. Gene
  3. Defa1 - defensin, alpha 1 Gene

Defa1 - defensin, alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Defcr; Defcr1

Gene ID: 13216 | Gene type: protein coding

About Defa1

Summary

Acts upstream of or within response to bacterium and response to xenobiotic stimulus. Located in extracellular space. Is expressed in crypt of Lieberkuhn of jejunum; ileum; and intestine. [provided by Alliance of Genome Resources, Apr 2022]

Defa1 Products(1)

mRNA Protein Name
NM_010031.2 NP_034161.2 alpha-defensin 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to lipopolysaccharide IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to Gram-negative bacterium IGI
IGI: Inferred from genetic interaction
17273556 MGI
acts upstream of or within defense response to Gram-positive bacterium IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
7927786 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
11248802 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
11248802 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-defensin 1

cryptdin-1

defensin related cryptdin peptide 1

defensin-1

defensin-related cryptdin peptide

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03673 DEFA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defa1 NCBI NCBI:1667