CFAP251 - cilia and flagella associated protein 251 Gene

Also Known as WDR66; SPGF33; CaM-IP4

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 144406

Summary

This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]

CFAP251 Products (1)

mRNA Protein Name
NM_001178003.2 NP_001171474.1 cilia- and flagella-associated protein 251 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
30122540 GOA
Cellular Component GO Annotation Evidence References Source
located in sperm flagellum IDA
IDA: Inferred from direct assay
30122540 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cilia- and flagella-associated protein 251

  • WD repeat domain 66

  • WD repeat-containing protein 66