CD300LG - CD300 molecule like family member g Gene

Also Known as CLM9; CLM-9; TREM4; TREM-4; NEPMUCIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 146894

About CD300LG

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:43,847,176-43,863,639 (from NCBI)

This gene has 8 transcripts (splice variants), 87 orthologues and 13 paralogues. Biased expression in fat (RPKM 45.4), placenta (RPKM 12.3) and 3 other tissues.

Summary

Members of the CD300 (see MIM 606786)-like (CD300L) family, such as CD300LG, are widely expressed on hematopoietic cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like domain (Takatsu et al., 2006 [PubMed 16876123]).[supplied by OMIM, Mar 2008]

CD300LG Products (5)

mRNA Protein Name
NM_001168322.2 NP_001161794.1 CMRF35-like molecule 9 isoform 4 precursor
NM_001168323.2 NP_001161795.1 CMRF35-like molecule 9 isoform 3 precursor
NM_001168324.2 NP_001161796.1 CMRF35-like molecule 9 isoform 2 precursor
NM_001411122.1 NP_001398051.1 CMRF35-like molecule 9 isoform 5 precursor
NM_145273.4 NP_660316.2 CMRF35-like molecule 9 isoform 1 precursor

CD300LG Protein Structure

V-set

V-set: Immunoglobulin V-set domain (21 - 112)

  • 0
  • 100
  • 200
  • 300
  • 332 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 9

  • CD300 antigen-like family member G

CD300LG Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CD300LG Q6UXG3 KRTAP10-9 Homo sapiens P60411
Y2H Array
25416956
Intra
CD300LG Q6UXG3 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
25416956
Intra
CD300LG Q6UXG3 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
CD300LG Q6UXG3 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
CD300LG Q6UXG3 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Prey Pooling
32296183
Intra
CD300LG Q6UXG3 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Array
32296183
Intra
CD300LG Q6UXG3 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
CD300LG Q6UXG3 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD300LG Proteins

Cat. No. Product Name Accession Purity
HY-P74247 CLM9/CD300g Protein, Human (HEK293, Fc) Q6UXG3-1 (L19-R247) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P74248 CLM9/CD300g Protein, Human (HEK293) Q6UXG3-1 (L19-R247) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02232 CD300LG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19276 Cd300lg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25765 Cd300lg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CD300LG VGNC VGNC:38948
Mus musculus CD300LG MGD MGI:1289168
Rattus norvegicus CD300LG RGD RGD:1584376
Felis catus CD300LG VGNC VGNC:98782
Bos taurus CD300LG VGNC VGNC:27024
Macaca mulatta CD300LG VGNC VGNC:70915
Others CD300LG NCBI