AMZ1 - archaelysin family metallopeptidase 1 Gene

Homo sapiens

Gene ID: 155185 | Gene type: protein coding

About AMZ1

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:2,679,522-2,765,138 (from NCBI)

This gene has 7 transcripts (splice variants), 117 orthologues and 1 paralogue. Biased expression in brain (RPKM 1.1), endometrium (RPKM 0.6) and 7 other tissues.

Summary

Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]

AMZ1 Products(8)

mRNA	Protein	Name
NM_001284355.4	NP_001271284.1	archaemetzincin-1 isoform 2
NM_001321766.2	NP_001308695.1	archaemetzincin-1 isoform 3
NM_001384739.1	NP_001371668.1	archaemetzincin-1 isoform 4
NM_001384740.1	NP_001371669.1	archaemetzincin-1 isoform 5
NM_001384741.1	NP_001371670.1	archaemetzincin-1 isoform 6
NM_001384742.1	NP_001371671.1	archaemetzincin-1 isoform 7
NM_001384743.1	NP_001371672.1	archaemetzincin-1 isoform 1
NM_133463.4	NP_597720.1	archaemetzincin-1 isoform 1

AMZ1 Protein Structure

Peptidase_M54

0
100
200
300
400
498 a.a.

Protein Preferred Names

Protein Names

archaemetzincin-1

archeobacterial metalloproteinase-like protein 1

Related Diseases

Diseases

Alias

Myxosarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00675	AMZ1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	AMZ1	VGNC	VGNC:37842
Macaca mulatta	AMZ1	VGNC	VGNC:108388
Felis catus	AMZ1	VGNC	VGNC:59773
Rattus norvegicus	AMZ1	RGD	RGD:1311314
Bos taurus	AMZ1	VGNC	VGNC:25877
Mus musculus	AMZ1	MGD	MGI:2442258