AMZ1 - archaelysin family metallopeptidase 1 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 155185
About AMZ1
Cytogenetic location: 7p22.3
Genomic coordinates (GRCh38): 7:2,679,522-2,765,138 (from NCBI)
This gene has 7 transcripts (splice variants), 117 orthologues and 1 paralogue. Biased expression in brain (RPKM 1.1), endometrium (RPKM 0.6) and 7 other tissues.
Summary
Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]
AMZ1 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| NM_001284355.4 | NP_001271284.1 | archaemetzincin-1 isoform 2 |
| NM_001321766.2 | NP_001308695.1 | archaemetzincin-1 isoform 3 |
| NM_001384739.1 | NP_001371668.1 | archaemetzincin-1 isoform 4 |
| NM_001384740.1 | NP_001371669.1 | archaemetzincin-1 isoform 5 |
| NM_001384741.1 | NP_001371670.1 | archaemetzincin-1 isoform 6 |
| NM_001384742.1 | NP_001371671.1 | archaemetzincin-1 isoform 7 |
| NM_001384743.1 | NP_001371672.1 | archaemetzincin-1 isoform 1 |
| NM_133463.4 | NP_597720.1 | archaemetzincin-1 isoform 1 |
AMZ1 Protein Structure
Peptidase_M54
Peptidase_M54: Peptidase family M54 (255 - 304)
- 0
- 100
- 200
- 300
- 400
- 498 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
archaemetzincin-1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Myxosarcoma |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00675 | AMZ1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | AMZ1 | VGNC | VGNC:37842 |
| Macaca mulatta | AMZ1 | VGNC | VGNC:108388 |
| Felis catus | AMZ1 | VGNC | VGNC:59773 |
| Rattus norvegicus | AMZ1 | RGD | RGD:1311314 |
| Bos taurus | AMZ1 | VGNC | VGNC:25877 |
| Mus musculus | AMZ1 | MGD | MGI:2442258 |
| Others | AMZ1 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service