Ifngr1 - interferon gamma receptor 1 Gene

Also Known as Ifgr; CD119; Ifngr; Nktar; IFN-gammaR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15979

Summary

Predicted to enable cytokine receptor activity. Involved in several processes, including astrocyte activation; negative regulation of amyloid-beta clearance; and positive regulation of macromolecule metabolic process. Acts upstream of or within defense response to virus. Predicted to be located in several cellular components, including dendrite; endoplasmic reticulum; and postsynaptic density. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; cerebral cortex; cranium; female reproductive system; and liver. Used to study osteoporosis. Human ortholog(s) of this gene implicated in asthma; hepatitis B; immunodeficiency 27A; immunodeficiency 27B; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifngr1 Products (1)

mRNA Protein Name
NM_010511.3 NP_034641.1 interferon gamma receptor 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in astrocyte activation IGI
IGI: Inferred from genetic interaction
17255335 MGI
acts upstream of or within defense response to virus IMP
IMP: Inferred from mutant phenotype
25268627 MGI
involved in microglial cell activation IGI
IGI: Inferred from genetic interaction
17255335 MGI
involved in negative regulation of amyloid-beta clearance IGI
IGI: Inferred from genetic interaction
17255335 MGI
involved in positive regulation of amyloid-beta formation IGI
IGI: Inferred from genetic interaction
17255335 MGI
involved in positive regulation of gene expression IGI
IGI: Inferred from genetic interaction
17255335 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: Inferred from genetic interaction
17255335 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon gamma receptor 1

  • IFN-gamma receptor 1

  • IFN-gamma-R-alpha

  • IFN-gamma-R1

  • INF-g receptor

  • interferon gamma receptor alpha-chain

Recombinant Ifngr1 Proteins

Cat. No. Product Name Accession Purity
HY-P72611 IFN-gamma R1/CD119 Protein, Mouse (HEK293, His) P15261 (A26-D253) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73133 IFN-gamma R1/CD119 Protein, Mouse (HEK293, Fc) P15261 (A26-D253) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17474 Ifngr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P10840 Tkip Inhibitor 95.16% Unkown
HY-RS06588 IFNGR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23932 Ifngr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifngr1 NCBI NCBI:3459