Acer1 - alkaline ceramidase 1 Gene

Also Known as Cer1; Asah3; Alkcdase1; 2310024P18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 171168

Summary

Enables N-acylsphingosine amidohydrolase activity. Involved in regulation of water loss via skin; sebaceous gland development; and sphingosine biosynthetic process. Acts upstream of or within ceramide catabolic process and regulation of lipid metabolic process. Located in endoplasmic reticulum. Orthologous to human ACER1 (alkaline Ceramidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Acer1 Products (1)

mRNA Protein Name
NM_175731.4 NP_783858.1 alkaline ceramidase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acylsphingosine amidohydrolase activity IDA
IDA: Inferred from direct assay
12783875 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ceramide catabolic process IDA
IDA: Inferred from direct assay
12783875 MGI
involved in ceramide catabolic process IMP
IMP: Inferred from mutant phenotype
27126290 MGI
acts upstream of or within regulation of lipid metabolic process IDA
IDA: Inferred from direct assay
12783875 MGI
involved in sebaceous gland development IMP
IMP: Inferred from mutant phenotype
27126290 MGI
acts upstream of or within sphingolipid metabolic process IDA
IDA: Inferred from direct assay
12783875 MGI
involved in sphingosine biosynthetic process IMP
IMP: Inferred from mutant phenotype
27126290 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12783875 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alkaline ceramidase 1

  • N-acylsphingosine amidohydrolase 3

  • acylsphingosine deacylase 3

  • alkCDase 1

  • alkaline cdase 1

  • maCER1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1488 Bradykinin (1-5) 99.46% Unkown
HY-P1032S2 Angiotensin I-13C6,15N (human, mouse, rat) TFA 99.76% Unkown
HY-114424A H-Ile-Pro-Pro-OH hydrochloride Inhibitor 99.66% Unkown
HY-105858 H-Ile-Trp-OH Inhibitor 98.04% Unkown
HY-P0095 Acetyl tetrapeptide-5 Inhibitor 99.42% Unkown
HY-N3470 Isomartynoside Inhibitor 99.60% Unkown
HY-114424 H-Ile-Pro-Pro-OH Inhibitor / Unkown
HY-N10860 5-O-beta-D-Glucopyranosylmyricanol Activator / Unkown
HY-P1032F Biotinyl-Angiotensin I (human, mouse, rat) / Unkown
HY-P4471 p-Hydroxyhippuryl-His-Leu / Unkown
HY-P4552 Hippuryl-Phe-Arg-OH Activator / Unkown
HY-P4654 H-Tyr-Lys-OH / Unkown
HY-RS00153 ACER1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175724 MBL-IN-6 Inhibitor / Unkown
HY-N15775 Ace-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acer1 NCBI NCBI:125981