Acetyl tetrapeptide-5
Based on 1 Customer Validation
Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care.
For research use only. We do not sell to patients.
- Purity: 99.42%
- CAS No.: 820959-17-9
- Formula: C20H28N8O7
- Molecular Weight:492.49
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Biological Activity
ACE-1[1]
Acetyl tetrapeptide-5 (100 μg/mL) inhibits angiotensin-converting enzyme 1 (ACE-1) activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 820959-17-9
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Appearance Solid
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Molecular Weight 492.49
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Formula C20H28N8O7
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Color White to off-white
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Sequence
Ac-β-{Ala}-His-Ser-His-OH
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Sequence Shortening
Ac-β-{Ala}-HSH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
DMSO : 25 mg/mL (50.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Yun Wu, et al. Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts. Skin Pharmacol Physiol. 2021;34(4):194-202. [Content Brief]
[2]. Lijuan Zhang, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009 Sep-Oct;27(5):485-94. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0305 mL | 10.1525 mL | 20.3050 mL | 50.7625 mL |
| 5 mM | 0.4061 mL | 2.0305 mL | 4.0610 mL | 10.1525 mL | |
| 10 mM | 0.2030 mL | 1.0152 mL | 2.0305 mL | 5.0762 mL | |
| 15 mM | 0.1354 mL | 0.6768 mL | 1.3537 mL | 3.3842 mL | |
| 20 mM | 0.1015 mL | 0.5076 mL | 1.0152 mL | 2.5381 mL | |
| 25 mM | 0.0812 mL | 0.4061 mL | 0.8122 mL | 2.0305 mL | |
| 30 mM | 0.0677 mL | 0.3384 mL | 0.6768 mL | 1.6921 mL | |
| 40 mM | 0.0508 mL | 0.2538 mL | 0.5076 mL | 1.2691 mL | |
| 50 mM | 0.0406 mL | 0.2030 mL | 0.4061 mL | 1.0152 mL |