Rad54l - RAD54 like (S. cerevisiae) Gene

Also Known as RAD54

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19366

Summary

Predicted to enable ATP-dependent DNA/DNA annealing activity and DNA translocase activity. Acts upstream of or within several processes, including determination of adult lifespan; double-strand break repair via homologous recombination; and response to ionizing radiation. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in alimentary system; brain ventricular layer; metencephalon rest of alar plate marginal layer; renal cortex; and vibrissa. Used to study sclerocornea. Human ortholog(s) of this gene implicated in breast cancer; disease of cellular proliferation; non-Hodgkin lymphoma; and pancreatic Cancer. Orthologous to human RAD54L (RAD54 like). [provided by Alliance of Genome Resources, Apr 2022]

Rad54l Products (3)

mRNA Protein Name
NM_001122958.1 NP_001116430.1 DNA repair and recombination protein RAD54-like
NM_001122959.1 NP_001116431.1 DNA repair and recombination protein RAD54-like
NM_009015.3 NP_033041.3 DNA repair and recombination protein RAD54-like

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA damage response IGI
IGI: Inferred from genetic interaction
19061978 MGI
acts upstream of or within DNA damage response IMP
IMP: Inferred from mutant phenotype
16428451 MGI
acts upstream of or within chromosome organization IGI
IGI: Inferred from genetic interaction
15175260 MGI
acts upstream of or within determination of adult lifespan IGI
IGI: Inferred from genetic interaction
19061978 MGI
acts upstream of or within double-strand break repair IGI
IGI: Inferred from genetic interaction
15175260 MGI
acts upstream of or within double-strand break repair via homologous recombination IGI
IGI: Inferred from genetic interaction
16428451 MGI
acts upstream of or within double-strand break repair via homologous recombination IMP
IMP: Inferred from mutant phenotype
19061978 MGI
acts upstream of or within response to ionizing radiation IGI
IGI: Inferred from genetic interaction
19061978 MGI
acts upstream of or within response to ionizing radiation IMP
IMP: Inferred from mutant phenotype
16428451 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
16428451 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA repair and recombination protein RAD54-like

  • RAD54 homolog

  • mHR54

  • mRAD54

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01252 ATRX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11612 RAD54L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11613 RAD54L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19577 Atrx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rad54l NCBI NCBI:8438