2. Gene
  3. Rps6ka1 - ribosomal protein S6 kinase polypeptide 1 Gene

Rps6ka1 - ribosomal protein S6 kinase polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rsk; Rsk1; Rsk-1; p90S6K; p90rsk; p90Rsk1; p90-Rsk1; Mapkapk-1a; S6K-alpha-1

Gene ID: 20111 | Gene type: protein coding

About Rps6ka1

Chromosome 4: 133,574,601-133,615,108 reverse strand.GRCm39:CM000997.3

This gene has 9 transcripts (splice variants), 218 orthologues, 7 paralogues and is associated with 2 phenotypes. Broad expression in duodenum adult (RPKM 79.7), colon adult (RPKM 69.8) and 24 other tissues.

Summary

Enables kinase activity. Involved in hepatocyte proliferation. Located in spindle. Is expressed in central nervous system; early conceptus; oocyte; and retina. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka1 Products(4)

mRNA Protein Name
NM_001285505.1 NP_001272434.1 ribosomal protein S6 kinase alpha-1 isoform b
NM_001285506.1 NP_001272435.1 ribosomal protein S6 kinase alpha-1 isoform c
NM_001378880.1 NP_001365809.1 ribosomal protein S6 kinase alpha-1 isoform d
NM_009097.5 NP_033123.2 ribosomal protein S6 kinase alpha-1 isoform a

Rps6ka1 Protein Structure

STKc_RSK_N

STKc_RSK_N: cd05582 (65 - 381)

STKc_RSK1_C

STKc_RSK1_C: cd14175 (415 - 705)

  • 0
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  • 600
  • 735 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase alpha-1

90 kDa ribosomal protein S6 kinase 1

MAP kinase-activated protein kinase 1a

MAPK-activated protein kinase 1a

MAPKAP kinase 1a

ribosomal protein S6 kinase, 90kD, polypeptide 1

Ribosomal protein S6 kinase, 90kD, 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-123919 TL13-112 Inhibitor 98.15% Unkown
HY-122582 TL13-12 Inhibitor 98.06% Unkown
HY-148061 DB1113 99.28% Unkown
HY-136194 TL13-22 Inhibitor / Unkown
HY-136195 TL13-110 Inhibitor / Unkown
HY-RS12248 RPS6KA1 Human Pre-designed siRNA Set A / Unkown
HY-RS12249 Rps6ka1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12250 Rps6ka1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6ka1 NCBI NCBI:6195