TL13-22
Based on 1 Customer Validation
TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells.
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 2229036-65-9
- Formula: C45H55ClN10O9S
- Molecular Weight:947.50
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Heterocyclic Compound Library
HY-L138
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Membrane Protein-targeted Compound Library
HY-L149
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
IC50: 0.54 nM (ALK)[1]
Chemical Information
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CAS No. 2229036-65-9
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Appearance Solid
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Molecular Weight 947.50
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Formula C45H55ClN10O9S
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Color Light yellow to yellow
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SMILES
O=C(NCCOCCOCCN1CCN(C2=CC=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3)C(OC)=C2)CC1)CNC5=CC=CC(C(N6C7C(NCCC7)=O)=O)=C5C6=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (263.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0554 mL | 5.2770 mL | 10.5541 mL | 26.3852 mL |
| 5 mM | 0.2111 mL | 1.0554 mL | 2.1108 mL | 5.2770 mL | |
| 10 mM | 0.1055 mL | 0.5277 mL | 1.0554 mL | 2.6385 mL | |
| 15 mM | 0.0704 mL | 0.3518 mL | 0.7036 mL | 1.7590 mL | |
| 20 mM | 0.0528 mL | 0.2639 mL | 0.5277 mL | 1.3193 mL | |
| 25 mM | 0.0422 mL | 0.2111 mL | 0.4222 mL | 1.0554 mL | |
| 30 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8795 mL | |
| 40 mM | 0.0264 mL | 0.1319 mL | 0.2639 mL | 0.6596 mL | |
| 50 mM | 0.0211 mL | 0.1055 mL | 0.2111 mL | 0.5277 mL | |
| 60 mM | 0.0176 mL | 0.0880 mL | 0.1759 mL | 0.4398 mL | |
| 80 mM | 0.0132 mL | 0.0660 mL | 0.1319 mL | 0.3298 mL | |
| 100 mM | 0.0106 mL | 0.0528 mL | 0.1055 mL | 0.2639 mL |
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