2229036-65-9
Chemical Structure
TL13-22
- CAS No.: 2229036-65-9
- Formula:C45H55ClN10O9S
- Molecular Weight:947.50
IUPAC Name: N-(2-(2-(2-(4-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
InChIKey: JVBGYTWMZKXATO-UHFFFAOYSA-N
SMILES: O=C(NCCOCCOCCN1CCN(C2=CC=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3)C(OC)=C2)CC1)CNC5=CC=CC(C(N6C7C(NCCC7)=O)=O)=C5C6=O
Biological Activity: TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TL13-22 | 99.71% | TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells. | ||||||||||||||||||||
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Keywords
