Heatr1 - HEAT repeat containing 1 Gene

Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of rRNA processing; and positive regulation of transcription by RNA polymerase I. Predicted to be located in fibrillar center and mitochondrion. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Is expressed in several structures, including brain ventricular layer; pectoral girdle and thoracic body wall muscle; physiological umbilical hernia; submandibular gland primordium; and thymus primordium. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]