Tsix - X (inactive)-specific transcript, opposite strand Gene

Species: Mus musculus

Gene Type: ncRNA
Gene ID: 22097

Summary

Acts upstream of or within epigenetic maintenance of chromatin in transcription-competent conformation; inactivation of paternal X chromosome; and negative regulation of transcription by RNA polymerase II. Is expressed in several structures, including early conceptus; liver; and retina nuclear layer. Orthologous to human TSIX (TSIX transcript, XIST antisense RNA). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24268575 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
21172659 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inactivation of paternal X chromosome by genomic imprinting IGI
IGI: Inferred from genetic interaction
15992549 MGI
acts upstream of or within inactivation of paternal X chromosome by genomic imprinting IMP
IMP: Inferred from mutant phenotype
15992549 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21029862 MGI
acts upstream of or within transcription initiation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
15992549 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Orthologs Information

Species Symbol Source ID
Homo sapiens Tsix NCBI NCBI:9383