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RBM24 - RNA binding motif protein 24 Gene

Also Known as RNPC6; dJ259A10.1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 221662

About RBM24

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:17,281,361-17,293,871 (from NCBI)

This gene has 8 transcripts (splice variants), 274 orthologues and 24 paralogues. Biased expression in heart (RPKM 42.8), endometrium (RPKM 14.9) and 4 other tissues.

Summary

Enables mRNA 3'-UTR AU-rich region binding activity; mRNA CDS binding activity; and sequence-specific mRNA binding activity. Involved in several processes, including negative regulation of cytoplasmic translation; positive regulation of cell differentiation; and regulation of mRNA metabolic process. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RBM24 Products (3)

mRNA	Protein	Name
NM_001143941.1	NP_001137413.1	RNA-binding protein 24 isoform 3
NM_001143942.2	NP_001137414.1	RNA-binding protein 24 isoform 1
NM_153020.2	NP_694565.1	RNA-binding protein 24 isoform 2

RBM24 Protein Structure

RRM_1

0
100
200
236 a.a.

Protein Preferred Names	Protein Names
RNA-binding protein 24	RNA-binding region (RNP1, RRM) containing 6

Related Diseases

Diseases	Alias
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11742	RBM24 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RBM24	MGD	MGI:3610364
Rattus norvegicus	RBM24	RGD	RGD:1584029
Macaca mulatta	RBM24	VGNC	VGNC:83456
Bos taurus	RBM24	VGNC	VGNC:33793
Others	RBM24	NCBI