Ascl5 - achaete-scute family bHLH transcription factor 5 Gene

Also Known as Gm197; AmeloD; bHLHa47; Ascl5-ps

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226439

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in genitourinary system; oral region epithelium; and tooth. Orthologous to human ASCL5 (achaete-scute family bHLH transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Ascl5 Products (1)

mRNA Protein Name
NM_001270609.2 NP_001257538.1 achaete-scute homolog 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
30426815 MGI
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
30426815 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
30426815 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
30426815 MGI
Biological Process GO Annotation Evidence References Source
involved in ameloblast differentiation IMP
IMP: Inferred from mutant phenotype
30504223 MGI
involved in amelogenesis IMP
IMP: Inferred from mutant phenotype
30504223 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
30426815 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
30426815 MGI
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase II transcription regulator complex IMP
IMP: Inferred from mutant phenotype
30426815 MGI
located in chromatin IDA
IDA: Inferred from direct assay
30426815 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

achaete-scute homolog 5

  • achaete-scute complex homolog 5, pseudogene

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01082 ASCL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ascl5 NCBI NCBI:647219