FNDC3A - fibronectin type III domain containing 3A Gene

Also Known as HUGO; FNDC3; bA203I16.1; bA203I16.5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 22862

About FNDC3A

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:48,975,291-49,209,779 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 11 paralogues. Ubiquitous expression in thyroid (RPKM 26.8), adrenal (RPKM 18.9) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to act upstream of or within several processes, including Sertoli cell development; fertilization; and spermatid development. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

FNDC3A Products (3)

mRNA Protein Name
NM_001079673.2 NP_001073141.1 fibronectin type-III domain-containing protein 3A isoform 1
NM_001278438.2 NP_001265367.1 fibronectin type-III domain-containing protein 3A isoform 1
NM_014923.5 NP_055738.3 fibronectin type-III domain-containing protein 3A isoform 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
18218838 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FNDC3A Protein Structure

fn3

fn3: Fibronectin type III domain (272 - 359)

fn3

fn3: Fibronectin type III domain (374 - 455)

fn3

fn3: Fibronectin type III domain (473 - 552)

fn3

fn3: Fibronectin type III domain (574 - 648)

fn3

fn3: Fibronectin type III domain (675 - 747)

fn3

fn3: Fibronectin type III domain (765 - 841)

fn3

fn3: Fibronectin type III domain (869 - 940)

fn3

fn3: Fibronectin type III domain (954 - 1035)

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  • 1000
  • 1198 a.a.
Protein Preferred Names Protein Names

fibronectin type-III domain-containing protein 3A

  • human gene expressed in odontoblasts

Related Diseases

Diseases Alias
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 3

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 3

  • EEC3

  • Eec Syndrome 3

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome, Type 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05019 FNDC3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FNDC3A VGNC VGNC:29062
Macaca mulatta FNDC3A VGNC VGNC:72539
Felis catus FNDC3A VGNC VGNC:62319
Rattus norvegicus FNDC3A RGD RGD:1304736
Canis familiaris FNDC3A VGNC VGNC:40928
Mus musculus FNDC3A MGD MGI:1196463
Others FNDC3A NCBI