Glrb - glycine receptor, beta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25456

Summary

Enables extracellularly glycine-gated ion channel activity and glycine binding activity. Involved in glycinergic synaptic transmission. Is active in glycinergic synapse. Human ortholog(s) of this gene implicated in hyperekplexia 2. Orthologous to human GLRB (glycine receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

Glrb Products (1)

mRNA Protein Name
NM_053296.2 NP_445748.1 glycine receptor subunit beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables extracellularly glycine-gated ion channel activity IDA
IDA: Inferred from direct assay
15574743 RGD
enables glycine binding IDA
IDA: Inferred from direct assay
15574743 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14976213 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
15574743 RGD
Biological Process GO Annotation Evidence References Source
involved in synaptic transmission, glycinergic IDA
IDA: Inferred from direct assay
15574743 RGD
Cellular Component GO Annotation Evidence References Source
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
22592841 RGD
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
22592841 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine receptor subunit beta

  • glycine receptor 58 kDa subunit

  • glycine receptor, beta subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05495 GLRB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22187 Glrb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28709 Glrb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glrb NCBI NCBI:2743