Igfbp6 - insulin-like growth factor binding protein 6 Gene

Also Known as RBP6A; RBP6G; IGF-BP6

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25641

Summary

Enables insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Predicted to be involved in cell migration; positive regulation of stress-activated MAPK cascade; and regulation of insulin-like growth factor receptor signaling pathway. Located in Golgi apparatus and extracellular space. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP6 (Insulin like growth factor binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp6 Products (1)

mRNA Protein Name
NM_013104.3 NP_037236.1 insulin-like growth factor-binding protein 6 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables insulin-like growth factor I binding IPI
IPI: Inferred from physical interaction
7689963 RGD
enables insulin-like growth factor II binding IPI
IPI: Inferred from physical interaction
7689963 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
7689963 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 6

  • IBP-6

  • IGF-binding protein 6

  • IGFBP-6

Recombinant Igfbp6 Proteins

Cat. No. Product Name Accession Purity
HY-P73905 IGFBP-6 Protein, Rat (HEK293, His) P35572/NP_037236.1 (A26-G226) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06629 IGFBP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174647 Human IGFBP6 mRNA / Unkown
HY-RS18710 Igfbp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25197 Igfbp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igfbp6 NCBI NCBI:3489